Fresh off the back of one Welsh Grand National win earlier this year, Synchronised is already the early 5-1 favourite to win it again giving him two Coral Welsh Nationals in a year after the entries were revealed on Wednesday.
As the race was rescheduled from its original December date, due to bad weather, it eventually took place in January, when the Jonjo-O'Neill-trained eight-year-old won it.
Synchronised has also made a promising return to action when finishing third behind Dynaste at Haydock last weekend.
Commenting on the entries, Dave Stevens of Coral said: “In all the years we have sponsored Wales's biggest race, no horse has managed to win it twice in one calendar year, but Synchronised made an eye-catching return over hurdles at the weekend, and heads the betting to give AP McCoy yet another new entry in the record books.”
A total of 79 entries have been made for the 3m5½f Grade 3, due to be staged at Chepstow on December 27.
Paul Nicholls, who last won the race in 2005 with L'Aventure, has entered Neptune Collonges, Niche Market and The Minack, the latter is one of three 10-1 co-second favourites. Also look out for the Gordon Elliott trained Beautiful Sound who is currently second favourite and hoping to go on to the Aintree Grand National in April 2012.